Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new study shows. While chemotherapy successfully treats tumours and extends patients lives, it is known that they do not work for everyone for long, since cancer cells rewire the mechanism by which they transform fuel into energy (metabolism) in order to avoid the treatments effects. Many of these medications are so-called antimetabolics, which disrupt cell processes necessary for tumour growth and survival.