Atletico has to overcome a one-goal deficit to eliminate bitter rival Real in the second leg of the Champions League last 16 tie on Wednesday to maintain a chance of capturing the European trophy it has never won.
Its city rival and record 15-time European champion won the first leg 2-1 with a crucial goal from Brahim Diaz to continue dominance of the Madrid derby on Europe's biggest stage.
A team from Madrid is likely to face Arsenal in the quarterfinals unless a miracle helps PSV Eindhoven come back from a massive 7-1 home loss in the first leg, the biggest victory in an away match in the knockout stage of the Champions League.
Another Premier League club, Aston Villa, has a comfortable two-goal cushion, ahead of the second leg against Club Brugge, while last season's runner-up Borussia Dortmund is evenly matched with Lille ahead of the second leg in France.
Madrid mastersAtletico has been beaten in the 2014 and 2016 Champions League finals and eliminated by Real in the 2015 ...