Both teams are without a number of first-choice players. Alex McCarthy replaces the injured Aaron Ramsdale in goal for Southampton, one of five changes from the defeat at Wolves a fortnight ago. Ryan Fraser, Tyler Dibling, Paul Onuachu and Flynn Downes replace Ryan Manning, Joe Aribo, Cameron Archer and the injured Jan Bednarek.
Liverpool make three changes from the 2-0 win over Aston VIlla. Conor Bradley covers for the injured Trent Alexander-Arnold at right-back; Cody Gakpo and Dominik Szoboszlai are preferred to Luis Diaz and Alexis Mac Allister.
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