Detroit (9-1) at Indianapolis (5-6) Sunday, 1 p.m. EST, Fox BetMGM NFL odds: Lions by 7 1/2. Against the spread: Lions 8-2, Colts 8-3. Series record: Colts lead 22-19-2. Last meeting: Colts beat Lions 41-21 in Detroit on Nov. 1, 2020.