Appointment of vaccine critic knocks some of world’s biggest drugmakers including Moderna, AstraZeneca and GSK

• Who is RFK Jr and what are his likely top priorities?
• Business live – latest updates

Investors in pharmaceutical companies are selling off stock after Donald Trump nominated the anti-vaccine activist Robert F Kennedy Jr to lead the US Department of Health and Human Services.

RFK Jr has embraced numerous health-related conspiracy theories, and is one of the most persistent and influential vaccine deniers in the US.