First such use of missiles came hours after Vladimir Putin lowered Moscow’s threshold for using nuclear weapons

• Russia-Ukraine war – latest news updates

Ukraine has fired US-made long-range missiles into Russia for the first time since the Biden administration lifted restrictions on their use, drawing a warning from Moscow that it would respond “accordingly”.

Russia’s defence ministry reported that Ukraine launched six US-made Atacms missiles targeting the south-western Bryansk region overnight. The ministry claimed that five of the missiles were shot down and another was damaged. The ministry added that debris from the rockets caused a fire at an unnamed military facility.