The Uruguay midfielder Manuel Ugarte will make his full debut for United. Marcus Rashford and Harry Maguire also return to the starting XI, with Kobbie Mainoo, Alejandro Garnacho and Matthijs de Ligt moved to the rotation seats in the dugout.

FC Twente make a couple of changes to the team that won 5-0 away to Almere on Sunday. The captain Ricky van Wolfswinkel, once of Norwich City, and Michel Vlap replace Daan Rots and Carel Elting.

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