First such use of missiles came hours after Vladimir Putin lowered Moscow’s threshold for using nuclear weapons

• Russia-Ukraine war – latest news updates

Ukraine has fired US-made long-range missiles into Russia for the first time since the Biden administration lifted restrictions on their use, drawing a warning from Moscow that it would respond “accordingly”.

Russia’s defence ministry said Ukraine launched six US-made Atacms missiles targeting the south-western Bryansk region overnight. Ukrainian president Volodomyr Zelenskyy did not directly confirm the Bryansk attack but said: “We now have Atacms, Ukrainian long-range capabilities, and we will use them.”